Madhouse produced a 4-episode OVA adaptation of various chapters of the manga in March 1999. The anime first aired as a miniseries on the TBS television network and was later sold on VHS and LaserDisc.
Urban Vision released the Pet Shop of Horrors anime in North America, initially across two VHS tapes (each available in either subtitled or dubbed format) in February 2000 and May 2000. It was then re-released in Feburary 2001, on a single DVD video that contained all four episodes and both language options. Sentai Filmworks had acquired the license in October 2008, with distribution by ADV Films. However, in 2009, A.D. Vision announced that it has shut down ADV Films and distribution rights were transferred to Section23 Films, who continues to distribute titles from Sentai. In the UK this will get its DVD release via MVM on August 2, 2010.
Episode 1 – Daughter – A rich couple has lost their only daughter, Alice. Fortunately, Count D is able to acquire a very rare species of rabbit that looks exactly like Alice. The couple is overjoyed and immediately takes the rabbit home. But their love for Alice makes them breach one of the contract's terms.
Episode 2 – Delicious – The popular idol singer Evangeline Blue and her manager Jason are about to be wed on a luxury ship when Evangeline "accidentally" falls overboard, her body never to be found. The heartbroken Jason travels to Count D's to pick up a pet that Eva had supposedly ordered. But to his surprise, the pet turns out to be a very large rare species of a fish but looks (to him at least) like a mermaid who looks exactly like Eva.
Episode 3 – Despair – Actor Robin Hendrix was a one-hit wonder. After the phenomenal success of his debut movie, Robin couldn't get any more acting jobs. It seemed he'd been stereotyped by the very role that made him famous. To top it off, his wife has left him. Robin loves keeping pet reptiles, and so he goes to Count D's to pick up an additional pet to cheer himself up. But Count D has something special for Robin: a very rare species of reptile known as Medusa for its lethal stare, with the face and upper body of a beautiful woman, but the lower half of a large lizard.
Episode 4 – Dual – Roger Stanford comes from a long line of successful politicians, but is considered the bad apple of the family due to his carefree and womanising ways. His faithful assistant, Kelly Vincent, is determined to make Roger the president of the United States, even if it means making a pact with the legendary animal called the Kirin, who grants the wish of its sovereign through the blood of others. Count D just happens to have one Kirin in stock.